South Carolina Pharmacy Registry & Compliance Directory

Comprehensive database of pharmacy locations across 46 counties

State Market Insights

By Category

All Pharmacies 1,108
Retail 894
Specialty 56
Hospital 43
LTC 65
MailOrder 13
Wholesale 7
Remote 30

Market Scale

Population 5,142,750
Density (all) /10k 2.15
Density (retail) /10k 1.74
Pharmacy Desert Counties 5
Avg. VigilScale™ 53/100
Avg. Enrollment Age 14 yrs

Chain Mix

Solo (1) 261
Small Group (2–9) 164
Mid Chain (10–49) 30
Large Chain (50+) 61
Mega Chain 591

Special Designations

Independent 262
Sterile Compounding 33
Tele-Pharmacy 31
Government Owned 19
Non-Profit 37
Top Chains WALGREENS 18% CVS 16% WALMART 10%

South Carolina Pharmacy Landscape

Quick Facts

Key regulatory requirements and practice standards

Pharmacist-Technician Ratio
State regulations require a pharmacist-to-technician ratio of 1:4 (2 must be certified) to maintain safe pharmacy operations.
Continuing Education
Pharmacists must complete 15 hrs annually (6 live) of continuing education to maintain active licensure.
Technician Requirements
Pharmacy technicians in this state must meet the following requirement: Registration required; certification for high ratio.
Intern Supervision
Pharmacy intern supervision follows this standard: 1:1.
Remote Pharmacy
Remote pharmacy work and telepharmacy services are governed by these rules: Data entry only.
Vaccine Authority
Pharmacist authority to administer vaccines: Protocol-based.

Regulatory Warnings

Compliance requirements and monitoring obligations

Pharmacist in Charge Notification
When a Pharmacist in Charge (PIC) changes, the pharmacy must notify the state board within the following timeframe: Immediately.
Prescription Monitoring Reporting
Prescription Monitoring Program (PMP) reporting requirements: Daily.
PMP Query Requirements
Before dispensing controlled substances, pharmacists must check the Prescription Monitoring Program: Mandatory for all controls.
Board Inspection Focus
State pharmacy board inspections frequently focus on: PIC must be 'physically present' at least 30 hours per week..

Top Cities by Pharmacy Count

Largest pharmacy markets in South Carolina

Browse by County

All counties sorted by pharmacy count

Charleston County 409,840 pop · 92 retail · 2.24 density
Greenville County 528,251 pop · 102 retail · 1.93 density
Richland County 416,161 pop · 63 retail · 1.51 density
Spartanburg County 330,119 pop · 64 retail · 1.94 density
Horry County 356,578 pop · 57 retail · 1.60 density
Lexington County 295,934 pop · 48 retail · 1.62 density
York County 282,987 pop · 47 retail · 1.66 density
Anderson County 204,592 pop · 43 retail · 2.10 density
Beaufort County 189,071 pop · 33 retail · 1.75 density
Aiken County 169,865 pop · 26 retail · 1.53 density
Florence County 137,015 pop · 29 retail · 2.12 density
Pickens County 131,106 pop · 26 retail · 1.98 density
Berkeley County 231,419 pop · 24 retail · 1.04 density
Dorchester County 162,139 pop · 21 retail · 1.30 density
Georgetown County 63,594 pop · 20 retail · 3.14 density
Lancaster County 97,611 pop · 17 retail · 1.74 density
Orangeburg County 84,159 pop · 15 retail · 1.78 density
Greenwood County 69,309 pop · 15 retail · 2.16 density
Sumter County 105,199 pop · 16 retail · 1.52 density
Darlington County 63,025 pop · 13 retail · 2.06 density
Oconee County 78,775 pop · 15 retail · 1.90 density
Laurens County 67,456 pop · 11 retail · 1.63 density
Bamberg County 13,311 pop · 5 retail · 3.76 density
Cherokee County 56,200 pop · 7 retail · 1.25 density
Kershaw County 65,779 pop · 8 retail · 1.22 density
Chesterfield County 43,536 pop · 5 retail · 1.15 density
Clarendon County 31,163 pop · 6 retail · 1.93 density
Colleton County 38,561 pop · 7 retail · 1.82 density
Marion County 29,212 pop · 6 retail · 2.05 density
Marlboro County 26,585 pop · 5 retail · 1.88 density
Dillon County 28,255 pop · 5 retail · 1.77 density
Edgefield County 26,181 pop · 5 retail · 1.91 density
Jasper County 29,444 pop · 5 retail · 1.70 density
Newberry County 37,918 pop · 5 retail · 1.32 density
Williamsburg County 30,879 pop · 4 retail · 1.30 density
Barnwell County 20,653 pop · 3 retail · 1.45 density
Chester County 32,171 pop · 4 retail · 1.24 density
Hampton County 18,890 pop · 3 retail · 1.59 density
Abbeville CountyPharmacy Desert 24,368 pop · 2 retail · 0.82 density
Allendale County 8,073 pop · 2 retail · 2.48 density
Fairfield CountyPharmacy Desert 20,942 pop · 2 retail · 0.96 density
Lee County 16,557 pop · 2 retail · 1.21 density
Saluda County 18,952 pop · 2 retail · 1.06 density
Union CountyPharmacy Desert 27,158 pop · 2 retail · 0.74 density
Calhoun CountyPharmacy Desert 14,145 pop · 1 retail · 0.71 density
McCormick CountyPharmacy Desert 9,612 pop · 0 retail · 0.00 density

* Pharmacy Desert: fewer than 1 retail pharmacy per 10,000 residents, based on 2026 NPI and ROPA billing data.